If I'm not mistaken, WINE is now capable of running 32-bit Windows binaries on 64-bit-only macOS as well, so that may also be an option particularly for more simple apps.
Even the 64-bit WINE can't run 32-bit apps on Catalina. Their website specifically says they support up to macOS-10.14. Apparently 64-bit WINE can run 64-bit Windos apps on Catalina, though.
I’m using a Mojave VM with VMWare Fusion on my laptop (that runs Catalina) on the rare occasion of needing to run 32bit apps. Install & setup was easy, without any problems. VMWare Fusion is a paid app, but VirtualBox should be able to do the same for free.
It's possible to get a Mojave VM up and running but it was nontrivial when I gave it a shot