I had a good friend whose first taste was uncut or nearly uncut China white while he was in Viet Nam. He kicked when he got back stateside in 1970, then used again for a time in the late '70s. He drank a lot and used cocaine at different times, too. He died of liver failure this spring at the ripe age of 62. I tend to believe the alcohol did most of the damage, but he thought the powders contributed a lot to it too. Hard to say without some kind of controlled study on a large population, I suppose. My scientific curiosity doesn't extend far enough to make such a study worth it.