I'm not a specialist but I think there are some stapled peptides that do show ap...

JumpCrisscross · 2026-02-11T06:09:57 1770790197

> this review reports bioavailability of up to 70% for some agents

To save us some skimming, could you specify which ones? (The review covers cyclic peptides that are absorbed by all mammals.)

bonsai_spool · 2026-02-11T06:55:35 1770792935

There are several - I’m not sure why you say cyclic peptides are somehow distinct from other peptides regarding their bioavailability?

All peptides face similar challenges with absorption; the cyclic peptides simply have less liability to proteolysis.

The text covers dozens of agents with varied biochemical properties.