It definitely varies from person to person. I'm on the more sensitive side of tasting bitter substances, although I do like bitter foods like Brussels sprouts, grapefruit and kumquats, and I'm okay when food is sometimes bitter, as happens with cucumbers and eggplant, but when foods that aren't normally bitter are sweetened with bitter sweeteners, I really don't like them, even if it's a natural sweetener, like stevia.
Monk fruit is quite expensive, so I'm afraid it will not become very popular in commercial products like candy bars and soft drinks. But for DIY it is certainly a nice option.
Compared to what? Aspartame is almost certainly the most studied artificial sweetener in existence, and the safety profile looks very good.